Metformin sensitizes insulin signaling t
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Soo Kyung Lee; Jung Ok Lee; Ji Hae Kim; Su Jin Kim; Ga Young You; Ji Wook Moon;
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Article
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2011
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John Wiley and Sons
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English
β 911 KB
## Abstract Insulin resistance is the primary cause responsible for type 2 diabetes. Phosphatase and tensin homolog (PTEN) plays a negative role in insulin signaling and its inhibition improves insulin sensitivity. Metformin is a widely used insulinβsensitizing drug; however, the mechanism by which