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Soy phytoestrogens decrease the estrogenic activity of estradiol in an in vitro bioassay using a human endometrial cell line

✍ Scribed by M.J Murray; B.A Lessey


Book ID
119415703
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
22 KB
Volume
73
Category
Article
ISSN
1556-5653

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L Y I 17018 is a non-steroid anti-estrogen which exhibits about 100 times higher affinity for estrogen receptor than tamoxifen, another anti-estrogen. The cell line ES-I , which was isolated from human breast cancer MCF-7 cells, was highly sensitive to the cytocidal action of estradiol. Growth of ES