## Abstract Soy and its constituent isoflavone genistein inhibit the development and progression of prostate cancer (PCa). Our study in both cultured cells and PCa patients reveals a novel pathway for the actions of genistein, namely the inhibition of the synthesis and biological actions of prostag
Soy isoflavone genistein in prevention and treatment of prostate cancer
✍ Scribed by Perabo, F G E; Von Löw, E C; Ellinger, J; von Rücker, A; Müller, S C; Bastian, P J
- Book ID
- 121436314
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 121 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1365-7852
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## Abstract Genistein is a major component of soybean isoflavone and has multiple functions resulting in antitumor effects. Prostate cancer is 1 of the targets for the preventive role of genistein. We examined the effect of genistein on human prostate cancer (LNCaP and PC‐3) cells. Proliferation of
## BACKGROUND. Epidemiological surveys recorded that men in the Orient (Japan and China) consuming diets high in soy food were at low risk of developing clinical prostate cancer, compared to a relatively high risk among men in the West who consumed diets low in soy food. Soybeans contain phytoestr