Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking
β Scribed by N.L. Benowitz; S. Zevin; P. Jacob
- Book ID
- 108640001
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 304 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0306-5251
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria. The patients were given a single dose of 2 mg nicotine from the nasal spray with and without concurrent administration of a nasal vaso
Platelets of healthy smokers and nonsmokers were prepared and their content of 5-hydroxytryptamine was determined by HPLC with electrochemical detection. Platelet 5-HT levels in smokers (728 \_+ 156 pmol per 10 s platelets, mean\_+ SEM, n=9) were significantly higher than those in non-smokers (353\_