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Sources of error in the spike-triggered averaging method of motor unit number estimation (MUNE)

✍ Scribed by Dr. Mark B. Bromberg; Judith L. Abrams


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
652 KB
Volume
18
Category
Article
ISSN
0148-639X

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Reproducibility of the spike-triggered averaging technique of motor unit estimation (MUE) was assessed in biceps-brachialis muscle in 10 normal subjects and 15 subjects with amyotrophic lateral sclerosis (ALS). MUE was calculated by dividing the compound muscle action potential by the mean amplitude

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Spike-triggered averaging (STA) has been used to extract twitch profiles of single motor units (SMU) within the human masseter muscle. However, the reported twitch tensions may have been biased by the voluntary firing frequency of the SMUs, the complex architecture of the muscle, and by the biomecha

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The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasion