Sources of and technical approaches for the abatement of tobacco specific nitrosamine formation in moist smokeless tobacco products
β Scribed by Michael T. Fisher; Cliff B. Bennett; Alec Hayes; Yahya Kargalioglu; Brandy L. Knox; Dongmei Xu; Raheema Muhammad-Kah; Charles L. Gaworski
- Book ID
- 116464068
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 866 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0278-6915
No coin nor oath required. For personal study only.
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Reverse"-cigar smokers (who hold the burning end of cigars within the mouth), dippers (who place a mixture of Khainitobacco and slaked lime into the lower gingival groove) and users of tobacco-containing toothpaste (gudakhu) in Orissa, India, were examined for precancerous oral lesions, the frequenc
## Abstract A specific and rapid liquid chromatographic/tandem mass spectrometric (LC/MS/MS) method was developed and validated for NNAL, a metabolite of the tobaccoβspecific nitrosamine metabolite NNK. The metabolite was detected in smokers' urine with a limit of quantitation (LOQ) of 20 pg ml^β1^