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Source localization of averaged and single EEG spikes using the electric dipole model

โœ Scribed by Shinn-Yih Tseng; Fok-Ching Chong; Rong-Chi Chen; Te-Son Kuo


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
815 KB
Volume
17
Category
Article
ISSN
1350-4533

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โœฆ Synopsis


A scheme for localizing the epileptic focus is proposed. The scheme is on the basis of a model with an electric dipole inside a four-layer inhomogeneous sphen'cal model of head and utilizes a nonlinear programming algorithm applying the gradient projection method. Various initial estimates are used to prove the stability of the implemented dipole model. Fourteen single spike data and the averaged spike data are used to localize the epileptic focus. The results of the usage of the averaged spike data show that the dipole position is compatible with visual inspection of experienced clinical physicians. The results of the usage of the single spike show that 1 I of the 14 single spikes have dipole locations near the result of the averaged spike but the estimated dipole moments dffm markedly from one another. The localization results of the other three single spikes show that the dipole position is strongly affected by the background LEG. This kind of interfaence generally causes the eccentricity of the dipole to d&ate from its anatomically meaningful value. According to our results, the electn'c dipole model is roncluded to be valuable for the clinical application of localizing epileptic foci.


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