Theory of Evolutionary Molecular Enginee
✍
TAKUYO AITA; YUZURU HUSIMI
📂
Article
📅
2000
🏛
Elsevier Science
🌐
English
⚖ 334 KB
We examined the e!ectiveness of an &&adaptive leap'' strategy using the &&mutation scrambling'' method as an e$cient optimization technique (Uchiyama, 2000; J. Biochem. 128, 441}447) for cases where mutational (rough) additivity holds in "tness. The mutation scrambling method is composed of the foll