Sorption of human albumin and endotoxin on uncharged and charged ultrafiltration membranes made from polysulfone and polyethersulfone
✍ Scribed by Detlef Düputell; Eberhard Staude; Danuta Wyszynski
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 973 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0011-9164
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✦ Synopsis
Polysulfone-and polyethersulfone-based asymmetric ultrafiltration membranes were used for determining the influence of human albumin and endotoxin upon membrane performance. The membranes bore positive and negative charges. Human albumin was found to interact more strongly with the sulfonated than with aminated membranes. In the UF experiments the influence of the charges on retention and volume flow was investigated. The interactions of substrate and membrane were also investigated by electrokinetic measurements. In the case of the endotoxin the sorption occurred under static conditions. Here the sorption was shown only by measuring the change in the membrane potential.