Kidney haemodynamics appear to change after the early phases of diabetic nephropathy: increases in glomerular filtration rate and in renal plasma flow have been widely reported, while kidney size is increased. As the renal kallikrein-kinin system has been demonstrated to regulate kidney blood circul
Sorbitol accumulation is altered in Type 1 (insulin-dependent) diabetes mellitus
β Scribed by J. I. Malone; G. Knox; C. Harvey
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 574 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0012-186X
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Hepatic and peripheral insulin sensitivity were investigated in five newly diagnosed Type 1 (insulin-dependent) diabetic subjects before and after 1 week of twice daily insulin therapy. Eight weight-matched control subjects were also studied. Hepatic glucose production and glucose utilization were m
The effect of glucagon infusion on hepatic glucose production during euglycaemia was evaluated in seven Type i (insulin-dependent) diabetic patients and in ten control subjects. In the diabetic subjects normoglycaemia was maintained during the night preceding the study by a variable intravenous insu