✦ LIBER ✦

Sorafenib: Where do we go from here?

✍ Scribed by Abby B. Siegel; Sonja K. Olsen; Arthur Magun; Robert S. Brown Jr

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 331 KB
Volume: 52
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.23633

No coin nor oath required. For personal study only.

✦ Synopsis

The approval of sorafenib as the first effective drug for the treatment of hepatocellular carcinoma (HCC) represents a milestone in the treatment of this disease. A better understanding of HCC pathogenesis has led to the development of several novel targeted treatments. HCC is treated in a uniquely multidisciplinary way requiring surgeons, hepatologists, interventional radiologists, and oncologists. This review describes the molecular pathogenesis of HCC, explores current and future treatments based on these pathways, and describes how these new therapies may augment existing approaches to HCC treatment.

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