Sorafenib reduces the percentage of tumo
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Ingrid M.E. Desar; J. (Hans) F.M. Jacobs; Christina A. Hulsbergen-vandeKaa; Wim
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Article
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2010
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John Wiley and Sons
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French
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## Abstract Tyrosine kinase inhibitors (TKIs) as sorafenib are known to reduce the number of immunosuppressive regulatory T cells (Tregs) in the peripheral blood and thereby shifting the immune balance to a more stimulating setting. The effect of sorafenib on intratumoural Tregs is unclear but impo