Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia

✍ Scribed by Peer, C. J.; Sissung, T. M.; Kim, A.; Jain, L.; Woo, S.; Gardner, E. R.; Kirkland, C. T.; Troutman, S. M.; English, B. C.; Richardson, E. D.; Federspiel, J.; Venzon, D.; Dahut, W.; Kohn, E.; Kummar, S.; Yarchoan, R.; Giaccone, G.; Widemann, B.; Figg, W. D.

• Book ID: 126690011
• Publisher: American Association for Cancer Research
• Year: 2012
• Tongue: English
• Weight: 609 KB
• Volume: 18
• Category: Article
• ISSN: 1078-0432
• DOI: 10.1158/1078-0432.CCR-11-2484