## Abstract **BACKGROUND**: Congenital rubella syndrome (CRS) has long been characterized by the triad of deafness, cataract, and cardiovascular malformations (CVMs). While initial reports identified patent ductus arteriosus (PDA) as the primary CVM in CRS, the exact nature of the CVMs found in CRS
Sonography of subependymal cysts in congenital rubella syndrome
β Scribed by C. Beltinger; H. Saule
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 471 KB
- Volume
- 148
- Category
- Article
- ISSN
- 0340-6997
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β¦ Synopsis
Two newborns with congenital rubella syndrome are reported. Cranial sonography demonstrated bilateral cystic lesions in the subependymal germinal matrix. Congenital rubella and cytomegalovirus (CMV) infections are the most common proven causes of subependymal cysts of nonhaemorrhagic origin in the newborn. The sonographic detection of these cysts should prompt an intensive search for congenital viral infections.
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Forty-five serum samples from 31 newborns and infants with the congenital rubella syndrome (CRS) were tested by immunoprecipitation to determine their antibody spectra to each of the structural proteins of rubella virus. Most sera (37/ 45) contained little or no E2 protein-specific antibody, but som
## Abstract Rubella and congenital rubella syndrome continue to be important health problems worldwide. The detection of rubella RNA directly in clinical specimens is a critical factor in early laboratory diagnosis of recent or congenital infection, in addition to detection of rubellaβspecific IgM.
## Abstract A total of 190 specimens from South Indian children aged 0β59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twentyβsix of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detect
Rubella infection during the first trimester of pregnancy can cause the congenital rubella syndrome (CRS). Patients with CRS were shown to have a decreased humoral and cellular immunity. It is not known whether asymptomatic newborns who had experienced intrauterine infection with rubella virus (RV)