Sonographic study of the development of fetal corpus callosum in a Chinese population

✍ Scribed by Hai-chun Zhang; Jie Yang; Zhong-ping Chen; Xiao-yan Ma

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 120 KB
• Volume: 37
• Category: Article
• ISSN: 0091-2751
• DOI: 10.1002/jcu.20531

✦ Synopsis

Abstract

Purpose

The observation of fetal corpus callosum (CC) is important for the prenatal sonographic assessment of fetal central nervous system development. The aim of this study was to investigate the development of normal Chinese fetal CC.

Method

CC measurements were performed using high‐resolution transabdominal sonography on 622 Chinese fetuses between 16 and 39 weeks' gestation. The correlation between CC size and gestational age was investigated.

Results

The fetal CC length increased in a linear fashion during pregnancy. The length of the CC as a function of gestational age was expressed by the following regression equation: length (mm) = −9.567 + 1.495 × gestational age (weeks) (r = 0.932, p < 0.001).

Conclusion

Knowledge of normal CC appearance may help identify developmental anomalies and enable accurate prenatal counseling. © 2008 Wiley Periodicals, Inc. J Clin Ultrasound, 2009