The two main peripheral nerve sheath tumors found in patients with neurofibromatosis, type 1 (NF1), are neurofibroma, a benign tumor, and malignant peripheral nerve sheath tumor (MPNST). The tumors are related in that most MPNSTs are thought to arise by malignant transformation of neurofibromas. Suc
Sonographic imaging of the peripheral nerves in a patient with neurofibromatosis type 1
✍ Scribed by Murat Kara; Alize Yılmaz; Sumru Özel; Levent Özçakar
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 223 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0148-639X
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## Communicated by Haig H. Kazazian One of the main features of neurofibromatosis type 1 (NF1) is benign neurofibromas, 10-20% of which become transformed into malignant peripheral nerve sheath tumors (MPNSTs). The molecular basis of NF1 tumorigenesis is, however, still unclear. Ninety-one tumors