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Sonographic evaluation of gallbladder kinetics: In vitro and in vivo comparison of different methods to assess gallbladder emptying

✍ Scribed by Bernd Wedmann; Gabriele Schmidt; Martin Wegener; Christoph Coenen; Dieter Ricken; Cornelia Dröge

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
832 KB
Volume
19
Category
Article
ISSN
0091-2751

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✦ Synopsis

Abstract

In an in vitro study, 10 gallbladders of adult pigs and 6 gallbladders of lambs, all removed immediately after slaughtering, were stimulated in a water bath by electric means to induce active contraction. Gallbladder emptying was followed by ultrasonography employing five measurement procedures: (1) gallbladder width, (2) longitudinal planimetry, (3) transverse planimetry, (4) ellipsoid method, and (5) sum of cylinders method.

In an in vivo investigation, gallbladder emptying of 30 volunteers (12) healthy subjects, 18 diabetics) was evaluated in the same way after ingestion of a fatty meal. Gallbladder width was found to be unsuitable to estimate the decrease in gallbladder volume due to a nonlinear relation of the parameters. Longitudinal planimetry tended to be less valid than transverse of planimetry in assessing gallbladder volume reduction.

The most valid estimation of gallbladder volume decreases was obtained by the two three‐dimensional procedures. However, in neither in vitro nor in vivo could a significant difference between the sum of cylinders method and the ellipsoid method in determining relative volume reduction be established.

We conclude that a three‐dimensional measurement procedure should be used for valid assessments of gallbladder motility. However, according to our data there is no advantage in using the time‐consuming sum of cylinders method compared to the simple ellipsoid method.

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