SONOGRAPHIC ASSESSMENT OF THE FETAL PALPEBRAL FISSURE SLANT—AN ADDITIONAL TOOL IN THE PRENATAL DIAGNOSIS OF SYNDROMES
✍ Scribed by GUNTHER MIELKE; KLAUS DIETZ; HEIKO FRANZ; IRWIN REISS; ULRICH GEMBRUCH
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 392 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0197-3851
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✦ Synopsis
Several syndromes and aneuploidies are associated with ocular abnormalities including up-and down-slanting palpebral fissures. We describe a technique for the sonographic assessment of the fetal palpebral fissure slant which was used in 70 normal pregnancies from 14 to 36 weeks of gestation. In a frontal view of the fetal face, the inferior angle between the palpebral fissure and the midline of the skull was determined. The median angle was 89 , with a range from 87 to 90 . In selected cases, sonographic assessment of the fetal palpebral fissure slant may be a helpful additional tool in the prenatal diagnosis of syndromes, as demonstrated in a fetus with Seckel syndrome associated with downslanting palpebral fissures and in a fetus with Down's syndrome associated with upslanting palpebral fissures. 1997 by John Wiley & Sons, Ltd.