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Sonogashira Coupling of Functionalized Trifloyl Oxazoles and Thiazoles with Terminal Alkynes: Synthesis of Disubstituted Heterocycles.

✍ Scribed by Neil F. Langille; Les A. Dakin; James S. Panek


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


πŸ“œ SIMILAR VOLUMES


Copper-Free Sonogashira Coupling of Acid
✍ Pravinβ€…R. Likhar; M.β€…S. Subhas; Moumita Roy; Sarabindu Roy; M.β€…Lakshmi Kantam πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 German βš– 157 KB

## Abstract Pd/C is used as an efficient catalyst for the copper‐free __Sonogashira__ coupling of acid chlorides and terminal alkynes to afford ynones in high yields (__Tablesβ€…1__ and __3__). Cyclization of (2‐methoxyaryl)‐substituted ynones induced by I~2~/ammonium cerium(IV) nitrate (CAN) at room