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Sonochemical Synthesis of Magnetic Protein Container for Targeted Delivery

โœ Scribed by Yongsheng Han; Darya Radziuk; Dmitry Shchukin; Helmuth Moehwald

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
244 KB
Volume
29
Category
Article
ISSN
1022-1336

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โœฆ Synopsis

Abstract

A new targeted delivery system was developed in this paper by depositing magnetic NPs on protein containers which were prepared by sonicating oil in a protein solution. The deposition was conducted by layerโ€byโ€layer technique and monitored by zeta potential measurement. Such prepared samples can be targeted delivery in an external magnetic field. The hydrophobic dye TPP, as a model of drug, was loaded in the containers by dissolution in the oil phase before sonication. The containers loaded with dye are stable and can sustain the deposition treatment without loss of dye due to the protection of protein nanoshells.

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