## Abstract Recent animal data suggest that the gut plays a far more important metabolic role than previously thought. During critical illness, disruption in bowel barrier function may result in a chronic hypermetabolic state and contribute to multiorgan failure. Animal studies have demonstrated th
Some studies of the bacterial flora associated with the mucosa of the human gastrointestinal tract
β Scribed by Peach, S. L. ;Tabaqchali, S.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 420 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0027-769X
No coin nor oath required. For personal study only.
β¦ Synopsis
Specimens of mucosal tissue of the small and large bowel obtained either by a colonoscope or during surgical operations were investigated quantitatively for their bacterial flora. A detailed prescription of the methodology using an anaerobic chamber is given. Most of the mucosal specimens of the small intestine as well as all the specimens of the large intestine contained bacteria (about 104 germsip). Predominantly, Bacteroides. gram-positive rods, and cocci were isolated. In contrast to the gut lumen flora anaerobic bacteria of the mucosal flora did not outnumber the aerobes. In patients with inflammatory bowel disease or with carcinoma of the colon the mucosal flora showed no demonstrable alterations even after undergoing e sulphonamide therapy.
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