✦ LIBER ✦

Some Reductive Transformations in the Furazano[3,4-d]pyridazine System. — Formation of 1,2-Dipyridazinyldiazene Derivatives

✍ Scribed by Lange, Jerzy ;Karolak-Wojciechowska, Janina ;Tondys, Hanna

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 514 KB
Volume: 1992
Category: Article
ISSN: 0947-3440
DOI: 10.1002/jlac.199219920195

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Hydrogenation of 4,7‐diarylfurazano[3,4‐d]pyridazine 1‐oxides 1 on palladized carbon or platinum oxide yielded 4,5‐diamino‐3,6‐diarylpyridazines 2 and trans‐1,2‐bis(5‐amino‐3,6‐diaryl‐pyridazin‐4‐yl)diazene 1‐oxides 3, readily converted by stannous chloride into trans‐1,2‐bis(5‐amino‐3,6‐diarylpyridazin‐4‐yl)diazenes 6. Reduction of 1 with sodium tetrahydroborate gave 4,7‐diarylfurazano[3,4‐d]pyridazines 5 and 4,7‐diaryl‐4,5‐dihydrofurazano[3,4‐d]pyridazine 1‐oxides 4. The crystal structures of 3a and 4a were solved by X‐ray analysis.

📜 SIMILAR VOLUMES

ChemInform Abstract: Perylene Derivative

ChemInform Abstract: Perylene Derivatives Formation in Reaction of 3-Bromobenzanthrone and 4-Bromonaphthalic Acid Derivatives with a Reduction System NiCl2—2,2′Bipyridyl (or 1,10-Phenanthroline)—Zn.

✍ N. Yu. Adonin; V. A. Ryabinin; V. F. Starichenko 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

ChemInform Abstract: On the Condensation

ChemInform Abstract: On the Condensation of 2,2-Difluoro-4-methylbenzo(d)-1,3,2- dioxaborines with Cyanoacetic Acid Derivatives. Formation and Transformation of 3-Cyano-4-methyl-benzo(b)pyran-2-ones and Their 2- Imine Precursors.

✍ H. BOUTOME; H. HARTMANN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

On the condensation of 2,2-difluoro-4-me

On the condensation of 2,2-difluoro-4-methyl-benzo[d]-1,3,2-dioxaborines with cyano acetic acid derivatives. Formation and transformation of 3-cyano-4-methyl-benzo[b]pyran-2-ones and their 2-imine precursors

✍ H. Boutome; H. Hartmann 📂 Article 📅 1997 🏛 Springer Vienna 🌐 English ⚖ 374 KB

Synthesis and Effects on the COX-1 and C

Synthesis and Effects on the COX-1 and COX-2 Activity in Human Whole Blood ex vivo of Derivatives Containing the [1]Benzothienol-[3, 2-d]pyrimidin-4-one Heterocyclic System

✍ Andrea Santagati; Giuseppe Granata; Agostino Marrazzo; Maria Santagati 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 2 views

ChemInform Abstract: Reaction of Isoeuge

ChemInform Abstract: Reaction of Isoeugenol with Formaldehyde in Basic Medium: Formation of trans-4-(4-Hydroxy-3-hydroxymethyl-5-methoxy) phenyl-5-methyl-1,3-dioxane and Its Transformation into the Tricyclo[5.2.2.02,6]undecane System.

✍ V. SINGH; S. PRATHAP 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views