a) DANGEROUS DRUGS Thc pullicntioii in thc 13iillctin of tlic IIenltli Orgaiiisntioii of the Lcnguc of Natioid of rcconiinciidcd incthocls for nssnyiiig thc contciit of niorphinc in opiurii nnd of cocninc in raw cocninc mid in coca leaves rlrcw genenil nttciitioii to scvcrnl matters of interest to chemists. Firstly, that in order to coiitrol tlic triiffc in clniigerous drugs, trustworthy iiictliods of niinlysis arc ~~cccss;iry and that, tlrcrcforc, chcriiists linvc a direct coiiccrn in IL mattcr of iiitcriintionnl iiiiportniicc ; uiitl sccontlly, tlint n t tlic tiiric whcii tlic inrcstigntioits were bcguii, published ~nctliotls of .generally rccognizcd vnlidity were not nvailnblc csocpt for pnrticuliir nrticles.
Diirigcrous drugs nrc not so tlcscrihccl because of their toxicity, but becniisc t h y nrc drugs of addiction or arc cnsily coiivcrtcd to sucli. Tlic dnngcr lies in the fiict tlint witli continucd use, progrcssivcly Inrgcr doses of tlic thug arc required to produce the rlesircd effect, niid physicul and morn1 dcgciicrntioii of tlic iiidivitlunl is likcly to ciisuc in the nbseiicc of iigid iiiedicnl cgntrol.
Cocrtine.-It may bc rccnllcd tlint coca Icnvcs coiitniii bases, such 11s tlic hpgrincs, along with tlic cocniiic (methyl-heiizoyl-ccgoiiiiic), ciaiinmyl-cocniiic (methylciiinniiiyl-ecgoniiic) wid tlic trusillines (mctliyl tx-rind iiictliyl fJ-triisillyl-ccgoiiim), but of tlicsc only tlic last five nrc ilniigcrous drugs since t h y yield ccgoiiiiic, niid this is subsequciitly convcrtcd to cocniiic comnicrcially.