Some of Nathan Mantel's contributions to epidemiology

✍ Scribed by Mitchell H. Gail

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 109 KB
• Volume: 18
• Category: Article
• ISSN: 0277-6715
• DOI: 10.1002/(sici)1097-0258(19991230)18:24<3389::aid-sim458>3.0.co;2-#

✦ Synopsis

Nathan Mantel's many contributions to epidemiology grew out of his role as a statistical consultant and collaborator. His abilities to understand scienti"c issues, appreciate their subtleties, and produce simple, compelling analyses were remarkable. Several of the procedures he developed to meet consulting needs remain widely used by statisticians and other researchers. Examples are presented to illustrate his approach and intuitive brilliance, including work on the evaluation of diagnostic tests, the Mantel}Haenszel procedure and its extensions, the use of a prospective logistic risk model to analyse case-control data, a method for evaluating aggregation of cancer disease sites in pairs of diseased relatives, and methods for detecting clustering of disease and temporal-spatial association of diseased cases.