Some observations on the blood levels of phenylalanine in dilute mice and a comparison between human phenylketonuria and the disease of mice homozygous for the dilute lethal gene

Free amino acid pool in the brain of mic

Free amino acid pool in the brain of mice homozygous for the gene “dilute lethal”

✍ Dr Simone Simler; S. Essayag; M. Ledig; C. Koehl; P. Mandel 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 382 KB

## Abstract The neurologic mutant “dilute lethal” (dl) mice, which reveal several neurologic and biochemical disturbances similar to human phenylketonuria, were used to investigate some aspects of amino acid disorder. We have studied the free amino pool in the brain of “dl” mice and of their contro