Some observations about effects of isologous splenic cells on lethally irradiated mice
β Scribed by J. Rerabek
- Book ID
- 112704583
- Publisher
- Springer
- Year
- 1960
- Tongue
- English
- Weight
- 247 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1420-682X
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Estradiol treatment of irradiated mice during repopulation of their spleens by endogenous hemopoietic cells reduced the number of myelocytic colonies and increased the numbers of erythropoietic and undifferentiated colonies. The in- hibitory effects of the hormone on myelopoiesis were not dependent
## Abstract The leukaemogenic effect of NβbutylβNβnitrosourea (BNU) was studied in normal and thymectomized AKR mice which were lethally irradiated and restored with either boneβmarrow (BM) or spleen cells from (AKR Γ AKR/T1ALD)F~1~ donors. In some instances T1ALD thymic cells were added to the res