Detection of crosslinks with the comet a
✍
Oliver Merk; Günter Speit
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
English
⚖ 90 KB
The alkaline comet assay is a sensitive test for the detection of a variety of DNA lesions. However, crosslinks are not readily detected under standard test conditions. Recently, modifications have been introduced measuring crosslinks by determining the reduction of induced DNA migration. We used th