Some equilibrium and non-equilibrium properties of the allosteric interactions in enzymes I. Ligand binding and saturation equations

✍ Scribed by P. Chuknyiski

• Publisher: Elsevier Science
• Year: 1974
• Tongue: English
• Weight: 491 KB
• Volume: 44
• Category: Article
• ISSN: 0022-5193
• DOI: 10.1016/s0022-5193(74)80033-0

✦ Synopsis

The binding of ligand to the protein was considered as a two-stage process. The collision of the ligand with the protein molecule and its penetration into the binding site were differentiated. The respective binding equations were given. It was indicated that the parameters in some of the equations could be determined by the experimental curves of ligand saturation and thus the two stages in ligand binding could be differentiated.