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Some behavioural signs of morphine withdrawal blocked by conditional stimuli

✍ Scribed by TYE, N. C.; IVERSEN, SUSAN D.


Book ID
109695509
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
312 KB
Volume
255
Category
Article
ISSN
0028-0836

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Sixty male hooded rats were made physically dependent on morphine by steadily increasing doses of morphine sulphate. A maintenance dose of w 400mg/kg/day was reached in 10 days and was continued for 5 additional days. At the end of the 15-day period all rats were withdrawn for 72 h and aggressive re