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Some behavioural effects of antidepressant drugs are time-dependent

✍ Scribed by Marta Dziedzicka-Wasylewska; Zofia Rogóż; Wojciech Margas; Daniel Dlaboga; Marta Góralska


Book ID
117448792
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
696 KB
Volume
25
Category
Article
ISSN
0278-5846

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In this study we investigated the effect of imipramine, citalopram and mianserin on behavioural effects of methoxamine, an a,-adrenoceptor agonist, in the rat. Methoxamine (25 and 50 pg) given into the brain lateral ventricle, increases the exploratory activity assessed in the open field test (time