BACKGROUND. The vascular system of the tumor bed plays an important function in tumor growth regulation. Recent studies have suggested that the vasoactive peptides somatostatin and substance P may have a potential role in the tumor bed of selected tumors. ## METHODS. In the current study, somatos
Somatostatin receptors and their subtypes in human tumors and in peritumoral vessels
β Scribed by Jean Claude Reubi; Jean-Claude Schaer; Jean A. Laissue; Beatrice Waser
- Book ID
- 117180019
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 268 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1532-8600
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Expression of mRNA for the 5 somatostatin receptors (sst 1-5 ) was characterized by Northern blot and RT-PCR analysis in 20 meningioma and 9 glioma samples. sst 1 mRNA was detectable by Northern blots of poly-A Ψ RNA in meningiomas but not gliomas. In contrast, sst 2 mRNA was readily detected by Nor
## Somatostatin receptor scintigraphy (SRS) is positive in approximately 80% of all patients who have been found to have neuroendocrine (NE) gastroenteropancreatic (GEP) tumors. The reasons for negative results are unclear. The aim of the present study was identification of the specific somatostat