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Somatostatin inhibition of adenylate cyclase activity in different brain areas

✍ Scribed by Gennaro Schettini; Tullio Florio; Olimpia Meucci; Elisa Landolfi; Maurizo Grimaldi; Carmelo Ventra; Adriano Marino

Book ID
115799607
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
552 KB
Volume
492
Category
Article
ISSN
0006-8993

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## Abstract Although alterations in adenylate cyclase (AC) activity and somatostatin (SRIF) receptor density have been reported in Alzheimer's disease, the effects of amyloid β‐peptide (AΞ²) on these parameters in the hippocampus are unknown. Our aim was to investigate whether the peptide fragment A