Somatostatin in the pancreas and hypothalamus of obese mice
β Scribed by J. Dolais-Kitabgi; Y. Le Marchand-Brustel; P. Freychet
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 460 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0012-186X
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The insulin, glucagon, somatostatin and pancreatic polypeptide content of acid-ethanol extracts of pancreas from lean and obese (ob/ob) mice of various ages was determined by radioimmunoassay. Rat and mouse pancreatic polypeptide react weakly with antibodies to avian, bovine and canine pancreatic po
Pancreatic somatostatin cells have been studied in human neonates and adults using an immunoperoxidase technique. Their volume density in the head, isthmus, corpus and tail of the gland has been estimated by morphometry. Somatostatin cells were about 20 times more frequent in the neonate (5% of all