Somatostatin hyperpolarizes neurons and inhibits spontaneous activity in the rat dorsolateral septal nucleus
โ Scribed by Michael J. Twery; Joel P. Gallagher
- Book ID
- 115799213
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 867 KB
- Volume
- 497
- Category
- Article
- ISSN
- 0006-8993
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The role of glucose in synaptic transmission was examined in the rat dorsolateral septal nucleus (DLSN) with single-microelectrode voltage-clamp and slicepatch techniques. Removal of glucose from the oxygenated Krebs solution caused a n outward current associated with an increased membrane conductan
Intracellular recordings were made from neurons in the dorsolateral septal nucleus (DLSN) of rat brain slices. Lowering the concentration of extracellular glucose resulted in a concentration-dependent membrane hyperpolarization associated with a cessation of spontaneous firing. The amplitude of the