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Somatostatin and analogs inhibit endogenous synaptic plasma membrane protein phosphorylation in vitro

✍ Scribed by Linda A. Dokas; Henk Zwiers; David H. Coy; Willem Hendrik Gispen


Book ID
115877578
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
789 KB
Volume
88
Category
Article
ISSN
0014-2999

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The time course of the phosphorylation o
✍ Malcolm Weller πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 637 KB

The phosphorylation of proteins in the synaptic plasma membrane is a rather slow reaction taking several minutes to saturate all the phosphate acceptor sites. (The time for half the protein bound phosphate groups to turnover is about 1 min). A divalent cation is needed as a cofactor for the reaction