Somatostatin activates an inwardly rectifying K+channel in neonatal rat atrial cells

Inwardly rectifying K+ (Kir) channels an

Inwardly rectifying K+ (Kir) channels antagonize ictal-like epileptiform activity in area CA1 of the rat hippocampus

✍ Mogens Andreasen; Jane Skov; Steen Nedergaard 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 493 KB 👁 1 views

## Abstract Reactive glial cells, for example, from patients with temporal lope epilepsy have a reduced density of inward rectifying K^+^ (Kir) channels and thus a reduced K^+^ buffering capacity. Evidence is accumulating that this downregulation of Kir channels could be implicated in epileptogenes