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Somatic mutations in human cancer—moving towards large scale resequencing of whole cancer genomes

✍ Scribed by A. Futreal


Book ID
103851042
Publisher
Elsevier
Year
2010
Tongue
English
Weight
46 KB
Volume
27
Category
Article
ISSN
1871-6784

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Recently, the genome sequences from several cancers have been published, along with the genome from a noncancer tissue from the same individual, allowing the identification of new somatic mutations in the cancer. We show that there is significant variation in the density of mutations at the 1-Mb sca