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Somatic mutations can lead to a loss of superantigenic and polyreactive binding

✍ Scribed by Pablo Oppezzo; Gérard Dumas; Jean-Pierre Bouvet; Carlos Robello; Alfonso Cayota; Juan Carlos Pizarro; Guillaume Dighiero; Otto Pritsch


Book ID
102165761
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
295 KB
Volume
34
Category
Article
ISSN
0014-2980

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A single mutation leads to loss of gluta
✍ D. W. MacDonald 📂 Article 📅 1982 🏛 Springer-Verlag 🌐 English ⚖ 606 KB

Glutamine synthetase activity in the ascomycete fungus Aspergillus nidulans is regulated by nitrogen source. The lowest activities are obtained when the fungus is grown on L-glutamine, and the highest activities when grown on L-glutamate + arabinose. Glutamine auxotrophs of the fungus have been isol