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Somatic mutation of the death domain of TNF-R1 is rare in common cancers

โœ Scribed by MIN SUNG KIM; HYUNG KYU YOON; IN SOOK WOO; SEUNG JOON KIM; NAM JIN YOO; SUG HYUNG LEE


Book ID
109343885
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
56 KB
Volume
117
Category
Article
ISSN
0365-5555

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It is now believed that genes regulating apoptosis are also important variables in cancer development. Fas, a transmembrane protein of the tumour necrosis factor receptor family, is a key molecule for cell death signalling. The mutation of the primary structure of the Fas gene might also be one of t