𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency

✍ Scribed by Bader, Scott; Walker, Marion; Hendrich, Brian; Bird, Adrian; Bird, Colin; Hooper, Martin; Wyllie, Andrew


Book ID
110062591
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
159 KB
Volume
18
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Systematic identification of genes with
✍ Stefan M. Woerner; Johannes Gebert; Yan P. Yuan; Christian Sutter; Ruediger Ridd πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 153 KB

Microsatellite instability (MSI) caused by deficient DNA mismatch-repair functions is a hallmark of cancers associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome but is also found in about 15% of all sporadic tumors. Most affected microsatellites reside in untranslated inter

Sequence analysis of the mismatch repair
✍ Jens Plaschke; Christian Kruppa; RenΓ© Tischler; Tina Bocker; Steffen Pistorius; πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 634 KB

To evaluate the involvement of hMSH6 in colorectal cancer, the complete coding sequence and flanking intron regions of the gene were analyzed by DNA sequencing in 10 patients fulfilling Bethesda Guidelines for colorectal tumors and 10 patients with sporadic colorectal carcinoma. In addition, 10 mono