Frequent somatic mutations of mitochondr
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Hiroshi Kumimoto; Yoshihiro Yamane; Yoshio Nishimoto; Hiroko Fukami; Masayuki Sh
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Article
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2003
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John Wiley and Sons
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French
โ 70 KB
## Abstract Recent studies of various cancers, such as those of the breast, head and neck, bladder and lung, reported that 46โ64% of somatic mutations in the Dโloop region of mitochondrial DNA (mtDNA) are observed. However, in esophageal cancer, only a low rate (5%) of somatic mutations has so far