SOMATIC CHROMOSOMES IN A CHILD WITH BONNEVIE-ULLRICH SYNDROME
β Scribed by Jacobs, Patricia; Keay, A.J.
- Book ID
- 122080523
- Publisher
- The Lancet
- Year
- 1959
- Tongue
- English
- Weight
- 162 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Using standard cytogenetic methods coupled with molecular techniques, the following karyotype mos 45,X/46,XXq+/46,X+mar (X)/47,XXq+,+mar(X), was identified in a patient with UllrichβTurner syndrome (UTS). Highβresolution banding (n = 650) of the metaphase chromosomes yielded a breakpoin
Cytogenetic studies have shown that 40-60% of patients with Ullrich-Turner syndrome (UTS) are 45,X, whereas the rest have structural aberrations of the X chromosome or mosaicism with a second cell line containing a structurally normal or abnormal X or Y chromosome. However, molecular analysis has de
We describe the cytogenetic evolution of multiple cell lines in the gonadal tissue of a 10-year-old girl with mosaic Ullrich-Turner syndrome (UTS) involving clonal telomeric associations (tas) of the Y chromosome. Gband analysis of all tissues showed at least 2 cell lines; 45, X and 46,X,tas(Y;21)(q