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Somatic cell hybrids producing antibodies specific to human fibronectin

✍ Scribed by Luciano Zardi; Barbara Carnemolla; Annalisa Siri; Leonardo Santi; Roberto S. Accolla

Book ID
102276635
Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
470 KB
Volume
25
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

We have produced somatic cell hybrids between mouse plasmocytoma cells deficient in hypoxanthine phosphoribosyltransferase (P3 Γ— 63 Ag8) and spleen cells derived from mice immunized with purified human plasma fibronectin. We report herein the properties of monoclonal anti‐fibronectin antibodies released by eight different clones.

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Monoclonal antibodies against mouse nerv
Monoclonal antibodies against mouse nerve growth factor produced by somatic cell hybrids
✍ Rita Businaro; Richard H. Butler; Allan E. Rubenstein; Roberto P. Revoltella πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 604 KB

## Abstract Spleen leukocytes from rats and mice immunized against mouse 2.5S nerve growth factor (NGF) and peripheral blood leukocytes from rabbits hyperimmunized against the same antigen were fused with the mouse plasmacytoma P3 Γ— 63Ag8. Hybridomas were screened by immunological assays (microcomp