✦ LIBER ✦

Somatic cell genetics of immunoglobulin production

✍ Scribed by Matthew D. Scharff

Book ID: 113132244
Publisher: Elsevier Science
Year: 1982
Tongue: English
Weight: 376 KB
Volume: 66
Category: Article
ISSN: 0008-8749
DOI: 10.1016/0008-8749(82)90153-8

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## Abstract The antigen receptor loci are the only loci in humans to undergo programmed somatic gene modification. Although aberrant V(D)J integration and class switch recombination can both give rise to chromosomal translocations, a role for somatic hypermutation in such genomic rearrangements has