Solvent Removal and Spore Inactivation Directly in Dispensing Vials with Supercritical Carbon Dioxide and Sterilant

Inactivation of bacterial spores and vir

Inactivation of bacterial spores and viruses in biological material using supercritical carbon dioxide with sterilant

✍ Qing-Qing Qiu; Patrick Leamy; Jennie Brittingham; Jason Pomerleau; Nimesh Kabari 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB

## Abstract The purpose of this study was to validate supercritical carbon dioxide (SC‐CO~2~) as a terminal sterilization method for biological materials, specifically acellular dermal matrix. In this study, bacterial spores, __Bacillus atrophaeus__, were inoculated onto porcine acellular dermal ma