𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Solvent Rearrangement in an Antigen—Antibody Interface Introduced by Site-directed Mutagenesis of the Antibody Combining Site

✍ Scribed by Xavier Ysern; Barry A. Fields; T.Narayan Bhat; Fernando A. Goldbaum; William Dall'Acqua; Frederick P. Schwarz; Roberto J. Poljak; Roy A. Mariuzza


Book ID
115626619
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
275 KB
Volume
238
Category
Article
ISSN
0022-2836

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Functional characterization of an anti-e
✍ Stéphane Coulon; Jean-Luc Pellequer; Thierry Blachère; Martine Chartier; Elisabe 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB

The high-affinity monoclonal anti-estradiol antibody 9D3 presents a specificity defect towards estradiol-3sulphate and 3-glucuronide conjugates incompatible with use in direct immunoassays. The corresponding single-chain variable fragment (scFv), cloned and produced in E. coli, exhibited a 10-fold l