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Solvent-Free Synthesis of Diphenyl [2-(Aminocarbonyl)-1,2-dihydroisoquinolin-1-yl]phosphonates from Isoquinoline, Isocyanates, and Diphenyl Phosphonate

✍ Scribed by Issa Yavari; Anvar Mirzaei; Gholamhossein Khalili

Publisher: John Wiley and Sons
Year: 2010
Tongue: German
Weight: 135 KB
Volume: 93
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200900247

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✦ Synopsis

Abstract

The 1 : 1 intermediates generated by addition of isoquinoline to isocyanates were trapped by diphenyl phosphonate to yield diphenyl [2‐(aminocarbonyl)‐1,2‐dihydroisoquinolin‐1‐yl]phosphonates in good yields under solvent‐free conditions.

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