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Solvent-free Synthesis of Alkylaminophenols via Petasis Boronic Mannich Reaction in One Pot without Catalysts

✍ Scribed by Ying Liu; Prof. Dr. Limin Wang; Yuanyuan Sui; Jianjun Yu

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 84 KB
Volume: 28
Category: Article
ISSN: 0256-7660
DOI: 10.1002/cjoc.201090340

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

By using solvent‐free and heat conditions, the Petasis boronic Mannich reaction of salicylaldehydes with various boronic acids and secondary amines without catalyst is described. The alkylaminophenols were obtained in moderate to good yields in a shorter reaction time than the traditional methods.

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