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Solvent-free synthesis of 5-methyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylic esters catalyzed by sulfamic acid

โœ Scribed by Changsheng Yao; Song Lei; Cuihua Wang; Chenxia Yu; Shujiang Tu


Publisher
Journal of Heterocyclic Chemistry
Year
2008
Tongue
English
Weight
214 KB
Volume
45
Category
Article
ISSN
0022-152X

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โœฆ Synopsis


Abstract

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The solventโ€free synthesis of 5โ€methylโ€7โ€arylโ€4,7โ€dihydrotetrazolo[1,5โ€a]pyrimidineโ€6โ€carboxylic esters was performed and effectively catalyzed by sulfamic acid. Compared with conventional methods, this protocol features mild reaction conditions and high yields. Furthermore, it is solventโ€free and thus ecoโ€friendly.


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