Solvent free oxidative radical substitution process. Synthesis of pyrrole fused systems

✍ Scribed by Edwin Flórez-López; Liliana B. Gomez-Pérez; Luis D. Miranda

• Book ID: 104098313
• Publisher: Elsevier Science
• Year: 2010
• Tongue: French
• Weight: 684 KB
• Volume: 51
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2010.09.025

✦ Synopsis

A xanthate-based, solvent free, homolytic substitution on selected substituted pyrrole systems is described. Additionally, a practical entry for the rapid construction of pyrrole fused systems using this solventless radical addition followed by a double nucleophilic alkylation sequence, is also reported.